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Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)
MASTER MODERN MEDICINE!
Introducing the Landmark Twentieth Edition of the Global Icon of Internal Medicine
The definitive guide to internal medicine is more essential than ever with the latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, hundreds of demonstrative full-color drawings, and practical clinical decision trees and algorithms
Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine gives you the informational foundation you need to provide the best patient care possible.
Essential for practice and education, the landmark 20th Edition features:

Thoroughly revised contentーcovering the many new breakthroughs and advances in clinical medicine that have occurred since the last edition of Harrison’s. Chapters on acute and chronic hepatitis, management of diabetes, immune-based therapies in cancer, multiple sclerosis, cardiovascular disease, HIV, and many more, deliver the very latest information on disease mechanisms, diagnostic options, and the specific treatment guidance you need to provide optimal patient care.
State-of-the-art coverage of disease mechanisms: Harrison’s focuses on pathophysiology with rigor, and with the goal of linking disease mechanisms to treatments. Improved understanding of how diseases develop and progress not only promotes better decision-making and higher value care, but also makes for fascinating reading and improved retention. Harrison’s summarizes important new basic science developments, such as the role of mitochondria in programmed and necrotic cell death, the immune system’s role in cancer development and treatment, the impact of telomere shortening in the aging and disease processes, and the role of the microbiome in health and disease. Understanding the role of inflammation in cardiovascular disease, the precise mechanisms of immune deficiency in HIV/AIDS, prions and misfolded proteins in neurodegenerative diseases, and obesity as a predisposition to diabetes are just a few examples of how this edition provides essential pathophysiology information for health professionals.
All-new sections covering a wide range of new and emerging areas of vital interest to all healthcare professionals. New sections include: Sex and Gender-based Issues in Medicine; Obesity, Diabetes Mellitus, and Metabolic Syndrome; and Consultative Medicineー Plus, a new Part covering cutting-edge topics in research and clinical medicine includes great new chapters on the role of Epigenetics in Health and Disease, Behavioral Strategies to Improve Health, Genomics and Infectious Diseases, Emerging Neuro-Therapeutic Technologies, and Telomere Function in Health and Disease, and Network System Medicine.
Important and timely new chaptersーsuch as Promoting Good Health, LGBT Health, Systems of Healthcare, Approach to Medical Consultation, Pharmacogenomics, Antimicrobial Resistance, Worldwide Changes in Patterns of Infectious Diseases, Neuromyelitis Optica, and moreーoffer the very latest, definitive perspectives on must-know topics in medical education and practice.
Updated clinical guidelines, expert opinions, and treatment approaches from world-renowned editors and authors contribute to the accuracy and immediacy of the text material and present a clear blueprint for optimizing patient outcomes.
End-of-chapter suggested readings reinforce the text material and provide a robust platform for further study and research.

MASTER MODERN MEDICINE!
Introducing the Landmark Twentieth Edition of the Global Icon of Internal Medicine
The definitive guide to internal ...
JPY 29,768
Brief Answers to the Big Questions
'A beautiful little book by a brilliant mind' Steven Poole, DAILY TELEGRAPH
The world-famous cosmologist and #1 bestselling author of A Brief History of Time leaves us with his final thoughts on the universe's biggest questions in this brilliant posthumous work.
Is there a God?
How did it all begin?
Can we predict the future?
What is inside a black hole?
Is there other intelligent life in the universe?
Will artificial intelligence outsmart us?
How do we shape the future?
Will we survive on Earth?
Should we colonise space?
Is time travel possible?
Throughout his extraordinary career, Stephen Hawking expanded our understanding of the universe and unravelled some of its greatest mysteries. But even as his theoretical work on black holes, imaginary time and multiple histories took his mind to the furthest reaches of space, Hawking always believed that science could also be used to fix the problems on our planet.
And now, as we face potentially catastrophic changes here on Earth - from climate change to dwindling natural resources to the threat of artificial super-intelligence - Stephen Hawking turns his attention to the most urgent issues for humankind.
Wide-ranging, intellectually stimulating, passionately argued, and infused with his characteristic humour, BRIEF ANSWERS TO THE BIG QUESTIONS, the final book from one of the greatest minds in history, is a personal view on the challenges we face as a human race, and where we, as a planet, are heading next.
A percentage of all royalties will go to charity.
'A beautiful little book by a brilliant mind' Steven Poole, DAILY TELEGRAPH
The world-famous cosmologist and #1 bestselling author of A Brie...
JPY 1,817
Ellen
ELLEN - THE NAKED MILF
Ellen – ganz offensichtlich kein Teenie mehr, knapp diesseits der dreißig, jedoch verführerisch und absolut geil anzusehen. Selbstsicherheit ausstrahlend, aber mit devoter Hingabe. Sie verführt Dich in jeder Situation, nicht nur visuell. Ihr fester Körper will von Dir genommen werden. Gehe mit ihr mit – in Deiner Phantasie – wohin auch immer
über 100 Fotos
ELLEN - THE NAKED MILF
Ellen – ganz offensichtlich kein Teenie mehr, knapp diesseits der dreißig, jedoch verführerisch und absolut geil anzu...
JPY 951
Unveiled! #114
Unveiled! – Witness these flawless living works of art being unveiled before your eyes. Watch the splendor in these awesome full-color pictures of gorgeous beauties as they bear their lovely physiques for your exclusive entertainment and satisfaction. These young and exquisitely sexy models are chiseled and sculptured to embody the essence of perfection.
The Unveiled! series brings an unbelievable presentation of mega-delicious vixens. These real-life models are gorgeous, hot, and better yet, they pose for you in excellent quality and full color! Enjoy these amazing beauties as they take you to the true boundaries of pleasure!
Imagicron Media guarantees you will get over 75 full-color images with greater quality than almost all other similar publications. These are not the small, crappy and blurry photos you are used to seeing everywhere. Even more, you get what’s advertised: no peek-a-boo, amateur, self-shot or teasing images; the clothes come fully off. You will get your money’s worth and you will likely come back for more.
This publication contains nudity and depictions of a sexual nature and is intended only for ADULT audiences.
Unveiled! – Witness these flawless living works of art being unveiled before your eyes. Watch the splendor in these awesome full-color pictu...
JPY 357
Unveiled! #118
Unveiled! – Witness these flawless living works of art being unveiled before your eyes. Watch the splendor in these awesome full-color pictures of gorgeous beauties as they bear their lovely physiques for your exclusive entertainment and satisfaction. These young and exquisitely sexy models are chiseled and sculptured to embody the essence of perfection.
The Unveiled! series brings an unbelievable presentation of mega-delicious vixens. These real-life models are gorgeous, hot, and better yet, they pose for you in excellent quality and full color! Enjoy these amazing beauties as they take you to the true boundaries of pleasure!
Imagicron Media guarantees you will get over 75 full-color images with greater quality than almost all other similar publications. These are not the small, crappy and blurry photos you are used to seeing everywhere. Even more, you get what’s advertised: no peek-a-boo, amateur, self-shot or teasing images; the clothes come fully off. You will get your money’s worth and you will likely come back for more.
This publication contains nudity and depictions of a sexual nature and is intended only for ADULT audiences.
Unveiled! – Witness these flawless living works of art being unveiled before your eyes. Watch the splendor in these awesome full-color pictu...
JPY 357
Unveiled! #116
Unveiled! – Witness these flawless living works of art being unveiled before your eyes. Watch the splendor in these awesome full-color pictures of gorgeous beauties as they bear their lovely physiques for your exclusive entertainment and satisfaction. These young and exquisitely sexy models are chiseled and sculptured to embody the essence of perfection.
The Unveiled! series brings an unbelievable presentation of mega-delicious vixens. These real-life models are gorgeous, hot, and better yet, they pose for you in excellent quality and full color! Enjoy these amazing beauties as they take you to the true boundaries of pleasure!
Imagicron Media guarantees you will get over 75 full-color images with greater quality than almost all other similar publications. These are not the small, crappy and blurry photos you are used to seeing everywhere. Even more, you get what’s advertised: no peek-a-boo, amateur, self-shot or teasing images; the clothes come fully off. You will get your money’s worth and you will likely come back for more.
This publication contains nudity and depictions of a sexual nature and is intended only for ADULT audiences.
Unveiled! – Witness these flawless living works of art being unveiled before your eyes. Watch the splendor in these awesome full-color pictu...
JPY 357
是男人沒有眼光,還是妳不懂得發光:這樣做球男人才接得到
戀愛教練AWE情感工作室創辦人Dana首度出書,教妳──女生該怎麼「脫單」?
比起滿滿的實際案例卻跟妳毫無關係,Dana用原則讓妳更有頭緒。
女人最常問的問題之一:好男人哪裡找? 
但是,怎樣的男人,對妳來說才是好男人? 在別人身邊的好男人,在妳身邊還會是好男人嗎? 一個男人之所以會是好男人或壞男人,取決於他遇到的女人。 所以,好男人要在妳自己身上找,而不是去外面找。 
戀愛教練AWE情感工作室創辦人Dana首度出書,教妳ーー女生該怎麼「脫單」? 比起滿滿的實際案例卻跟妳毫無關係,Dana用原則讓妳更有頭緒。 
脫單的起手式,談戀愛前先談自己ーー
比「男人喜歡什麼樣的女人」更重要的是,「妳是什麼樣的女人」? 
找不到合適對象可能不是因為生活圈太小而是妳不敢踏出生活圈; 可能不是總是被壞男人騙而是妳一直騙自己; 友達以上戀人未滿可能只是妳自己以為。 脫單的第二件事,解開對於男人的誤解 ーー理解「男人眼裡的女人美在哪裡」? 
男人視覺的關鍵不是胸部,而是「姿態」; 男人說的「喜歡」跟妳以為的喜歡不一樣; 男人要的識大體是「懂得替我留面子」。 避免脫單臨門一腳又瞬間恢單的注意事項 ーー維持長期關係的方式。 將自己當作獎品而非贈品,「做自己想做的事」並且坦然接受任何結果; 培養感情中的三個位置,彈性十足; 上床不會影響你們的關係,影響關係的是妳對上床的看法。
◎聯合推薦(順序依筆畫排列)
怪奇事務所 所 長
溝通表達培訓師/張忘形
大人學共同創辦人/張國洋
戀愛教練AWE情感工作室創辦人Dana首度出書,教妳──女生該怎麼「脫單」?
比起滿滿的實際案例卻跟妳毫無關係,Dana用原則讓妳更有頭緒。
女人最常問的問題之一:好男人哪裡找? 
但是,怎樣的男人,對妳來說才是好男人? 在別人身邊的好男人,在妳身邊還會是好男人嗎? 一個男人之所...
JPY 811
Lesbian Girls alone at Home
LESBIAN GIRLS ALONE AT HOME Wie heißt es so schön? Kaum ist die Katze aus dem Haus, da tanzen die Mäuse auf dem Dach. Und wie sie hier tanzen. Hier sehen Sie junge hübsche Girls, die sich flugs entblättern, um heiße Spiele mit ihresgleichen zu spielen. Sie schmiegen ihre knackigen Körper aneinander und kuscheln heftig miteinander. Erleben Sie tolle Bilder der lesbischen Liebe mit rassigen jungen Frauen.
LESBIAN GIRLS ALONE AT HOME Wie heißt es so schön? Kaum ist die Katze aus dem Haus, da tanzen die Mäuse auf dem Dach. Und wie sie hier tanze...
JPY 670
Bion and Meltzer's Expeditions into Unmapped Mental Life
Drawing on the influential contributions of Wilfred Bion and Donald Meltzer to psychoanalysis, Bion and Meltzer's Expeditions into Unmapped Mental Life explores and addresses the clinical implications of their work, both through revisiting several of their conceptions and illustrating them with detailed clinical material from the analyses of children, adolescents, and adults.
Psychoanalysis strives towards truth; this is its essence. However, emotional truth is often unknowable and not amenable to verbal communication. This ineffable mental realm is at the heart of both Bion and Meltzer's psychoanalytic endeavours.
Bion's writings reflect a developmental stage in the evolution of psychoanalysis, extending clinical work to mental realms that were seemingly unreachable. Donald Meltzer further infuses Bion's thinking with his own original notions of beauty and aesthetics, imbuing Bion's profound thinking with a poetic and lyrical tenor.
Writing in a clear and lucid manner, Avner Bergstein integrates Bion's sometimes highly theoretical thinking with everyday clinical practice, facilitating his dense and condensed formulations and making them clinically accessible and useful. Bion and Meltzer's Expeditions into Unmapped Mental Life is written for psychoanalysts and psychoanalytically oriented psychotherapists who are attracted to Bion and Meltzer's radical thinking.
Drawing on the influential contributions of Wilfred Bion and Donald Meltzer to psychoanalysis, Bion and Meltzer's Expeditions into Unmapped ...
JPY 4,428
Melville's Taxation: Finance Act 2018
This edition brings the book completely up to date with the provisions of Finance (No.2) Act 2017 and Finance Act 2018, including:
 
• Making Tax Digital (MTD) developments
• Scottish rates of income tax
• Reduction in the dividend allowance
• Gift Aid donor benefit rules
• Cash basis for property income
• Mileage rates for landlords
• Reforms to venture capital schemes
• Increase in the diesel supplement
• Increase in R&D expenditure credit
• Freezing of indexation allowance
• Reform of corporation tax loss relief
• Freezing of VAT registration threshold
This edition brings the book completely up to date with the provisions of Finance (No.2) Act 2017 and Finance Act 2018, including:
 
• Makin...
JPY 11,285
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